Due to abnormal metabolism, certain diseased tissues, most notably solid tumors, produce an acidic extracellular microenvironment that is still little understood. Nevertheless, today all drugs in oncology are developed by R&D teams using the same classic textbook definition of tumor acidity which leads to (among other issues) poor tumor targeting…

The explosion in computing resources over the last decade has made it possible for the extremely complex systems of molecular biology to be simulated in high enough fidelity to begin to produce new materials, new drugs and other important substances. However even with increasingly accurate simulation, chemical development today still…

Artificial intelligence has made significant strides in recent years, particularly with the rise of generative AI and large language models (LLMs). These innovations have sparked our collective imagination, turning once fictional concepts into tangible products used by companies at scale. However, the process of training these models is both resource-intensive…

Nanotechnology, core to the $200Bn value-added materials market, has for decades been heralded as one of the most promising areas of science and industry. However, we are yet to discover even 1% of what is possible in nanomaterial design because of the challenges in unlocking the unique properties of elements…

We are at the beginning of a new frontier in biology and medicine unparalleled in human history. Scientific advances like the latest generation of CRISPR, new computational methods, entirely new cell and gene therapies, cell-free synthetic biology and breakthroughs we cannot even imagine today will unlock the applications and treatments…

We are currently navigating an era that stands apart in the history of technological innovation. Multiple, rapidly-evolving disciplines, such as blockchain, Artificial Intelligence, web3, breakthrough engineering, and synthetic biology, are increasingly intersecting and influencing one another. This convergence is weaving a rich, complex tapestry of possibilities and challenges. In this…

We live in a time where the boundary between science fiction and reality is rapidly blurring. Scientists have used high-power lasers to reproduce the sun’s power on Earth, satellites launched by reusable rockets have made high-speed internet ubiquitous and affordable, and new computer architectures have accelerated super-human AI capabilities and…

The unprecedented speed and success of mRNA vaccines in tackling the COVID-19 pandemic has underscored the demand for mRNA as a next-generation nucleic acid therapy. Hundreds of ongoing clinical trials are currently testing mRNA across more than 20 disease categories. The current production process, called In Vitro Transcription (IVT), has…

In the wake of several high profile collapses among centralized players in the crypto world, DeFi is naturally receiving renewed attention as an alternative to centralized finance platforms. At BlueYard, we’re long-term believers in the potential of DeFi to deliver a superior coordination mechanism for the world’s financial activities. Despite…